Question: 3. Boner et al. [1] conducted a double-blind crossover study to compare the effects of nedocromil sodium 4 mg and placebo on exercise-induced bronchoconstriction in
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3. Boner et al. [1] conducted a double-blind crossover study to compare the effects of nedocromil sodium 4 mg and placebo on exercise-induced bronchoconstriction in 13 asthmatic children, the test treatments being given by pressurized aerosol using either the Auty-Altounyan (A-A) spacer device or the normal adapter. Treatment was given 15 minutes before exercise challenge. The response is the maximum fall in the forced expiratory volume in 1 second (FEV1) over the course of follow-up. The mean value and standard deviation for both experimental and control group are given below: Experimental Control Mean Standard Deviation Mean Standard Deviation 13.54 13.85 20.77 21.46 Answer the following questions according to the study: a. If the maximum fall in FEV, over the course of follow-up for the experimental group is statistically lower than 20.77, then the new treatment made a significant improvement. Conduct a hypothesis testing at 5% level of significance
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