A 38-year-old woman has had nausea for the past 6 months. She reports no vomiting or diarrhea.
Question:
A 38-year-old woman has had nausea for the past 6 months. She reports no vomiting or diarrhea. On physical examination, there are no remarkable findings. Upper gastrointestinal endoscopy shows diffuse gastric mucosal erythema with focal mucosal erosions, but no ulcerations. The esophageal and duodenal mucosal surfaces appear normal. Microscopic examination of gastric biopsy specimens shows increased numbers of neutrophils, lymphocytes, and plasma cells in the mucosa; edema; focal mucosal hemorrhage; and loss of the surface epithelium. No Helicobacter pylori organisms are seen. Laboratory studies show a normal serum gastrin level. Which of the following pharmacologic agents is most likely to produce these findings? ?
(A) Acetylsalicylic acid (aspirin)
(B) Acyclovir
(C) Chlorpromazine
(D) Cimetidine
(E) Clindamycin
Expert Answer:
The detailed answer for the above question is provided below option A These fi... View the full answer
