(a) Aspirin Tablet 13 23 C 3) 4) 39% EIGH FA gravity filiation + HO/cool vacuum...

  

Transcribed Image Text:

(a) Aspirin Tablet 13 23 "C 3) 4) 39% EIGH FA gravity filiation + HO/cool vacuum firation O OH (b)_ CH Question 1: If your Aspirin tablet is said to contain 5 grains of the active pharmaceutical ingredient (API) called acetylsalicylic acid (ASA) what is the expected mass of the API you would expect to isolate? (n.b. 1 grain = 65.0 mg) [15 points] Question 2: Provide (a) the starting mass of your Aspirin tablet (mg), (b) the amount of ASA recovered, (c) the calculated mass of excipients/binders that were not recovered, and (d) melting point ("C) of your isolated ASA. [20 points) scetylsalicylic acid CO, MW 180.16 (c). (d) Question 3: What is the percent isolation of the active pharmaceutical ingredient, ASA? Show the calculation with proper units and significant figures. (Note: percent isolation is mg of ASA recovered / manufacturer mg stipulated 100). [25 points) CHE 231L1-6-Organic Chemistry / Laboratory-Fall 2023 Question 4: Briefly describe the two major techniques gravity filtration and vacuum filtration that were utilized in this experiment and discuss why you would choose one method over the other. [20 points) Question 5: Describe some observations or techniques that you found fascinating. Discuss your melting point and what it means to a budding scientist, like you! Discuss how you might have lost material that could account for a low percent isolation (e.g., operational error like spilling, etc.): [20 points) Bonus: Draw the ester hydrolysis reaction of acetylsalicylic acid to give both salicylic acid and acetic acid. Then, identify the functional group(s) in each molecule that you drew. [+5 points] (a) Aspirin Tablet 13 23 "C 3) 4) 39% EIGH FA gravity filiation + HO/cool vacuum firation O OH (b)_ CH Question 1: If your Aspirin tablet is said to contain 5 grains of the active pharmaceutical ingredient (API) called acetylsalicylic acid (ASA) what is the expected mass of the API you would expect to isolate? (n.b. 1 grain = 65.0 mg) [15 points] Question 2: Provide (a) the starting mass of your Aspirin tablet (mg), (b) the amount of ASA recovered, (c) the calculated mass of excipients/binders that were not recovered, and (d) melting point ("C) of your isolated ASA. [20 points) scetylsalicylic acid CO, MW 180.16 (c). (d) Question 3: What is the percent isolation of the active pharmaceutical ingredient, ASA? Show the calculation with proper units and significant figures. (Note: percent isolation is mg of ASA recovered / manufacturer mg stipulated 100). [25 points) CHE 231L1-6-Organic Chemistry / Laboratory-Fall 2023 Question 4: Briefly describe the two major techniques gravity filtration and vacuum filtration that were utilized in this experiment and discuss why you would choose one method over the other. [20 points) Question 5: Describe some observations or techniques that you found fascinating. Discuss your melting point and what it means to a budding scientist, like you! Discuss how you might have lost material that could account for a low percent isolation (e.g., operational error like spilling, etc.): [20 points) Bonus: Draw the ester hydrolysis reaction of acetylsalicylic acid to give both salicylic acid and acetic acid. Then, identify the functional group(s) in each molecule that you drew. [+5 points]

Answer rating: 100% (QA)

Question 1 If your Aspirin tablet is said to contain 5 grains of the active pharmaceutical ingredien... View the full answer