Question: A case-control study is being planned to study the relationships between diabetes and Biomarker B among adults. Cases are defined as those who have diabetes,
A case-control study is being planned to study the relationships between diabetes and Biomarker B among adults. Cases are defined as those who have diabetes, and controls are those who do not have diabetes. The exposure variable is whether or not the individual has Biomarker B (yes/no). It is anticipated that 10% of controls (without diabetes) have Biomarker B, and the odds ratio (OR) that investigators would like to be able to detect is 2.0. They plan to carry out a 2-sided test with an alpha of 0.05 and desired power of 0.90.What value of zbeta should the researchers use in their sample size calculations
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