Question: A case-control study was conducted to assess the relationship between multiple sex partners and Kaposis sarcoma, a cancer transmitted by human herpesvirus 8.Cases were men

A case-control study was conducted to assess the relationship between multiple sex partners and Kaposis sarcoma, a cancer transmitted by human herpesvirus 8.Cases were men ages24 to 40 who had been diagnosed with Kaposis sarcoma during the six months prior to study recruitment.A group of men who had never been diagnosed with Kaposis sarcomawasselected asthecontrol.(25points)

Cases

Controls

Total

Multiple sex partners

Yes

201

109

310

No

116

344

460

Total

317

453

770

What are the odds ofcasesamongthe exposed (multiple sex partners:yes)?

What are the odds ofcasesamongthe non-exposed (multiple sex partners:no)?

Calculate and interpret the disease odds ratio for these data.

Calculate and interpret the 95% confidence interval for the above odds ratios.

Based on these data, would 3.75 be a reasonable estimate of the odds ratio of Kaposis sarcoma comparing men who have multiple sex partners with men who do not? Why or why not?

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