A gene encoding for the PERK receptor in mice has been knocked out or gets a mutation
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Question:
A gene encoding for the PERK receptor in mice has been knocked out or gets a mutation that leads to non-functional. It is known that this protein is required to detect misfolded proteins.
- What will be the problem during the quality control of protein?
- Is there any bypass to recover this problem?
Related Book For
Molecular Cell Biology
ISBN: 978-1429234139
7th edition
Authors: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Matthew P. Scott
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