Question: ( a ) Which two ( out of the three ) would be the best lead compounds? Why? ( b ) Describe the differences between

(a) Which two (out of the three) would be the best lead compounds? Why?(b) Describe the differences between the affinities and efficacies of the two compounds you selected in (a).
4. 100% 50% 11 1079 K = 10-9 M = 0.8 2

4. 100% 50% 11 1079 K = 10-9 M = 0.8 2 = 0.4 3 8 7 6 pkd (M) a = 1.0 Kd = 10-6 M 5

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