ACTIVITY: DOSAGE FORM DESIGN: PHARMACEUTICAL AND FORMULATION CONSIDERATIONS

List your answers to the following questions below:

1. List reasons for the incorporation of drugs into various dosage forms

2. Compare and contrast the advantages/disadvantages of various drug dosage forms

3. Describe the information needed in pre-formulation studies to characterize a drug substance for possible inclusion into a dosage form.

4. Describe the mechanisms of drug degradation and provide examples of each.

5. Describe the five types of drug instability of concern to the practicing pharmacist

6. Describe the purpose and general protocol for accelerated stability studies

7. Summarize approaches employed to stabilize drugs in pharmaceutical dosage forms.

8. Categorize various pharmaceutical ingredients and excipients.