answer a-b please read and answer correct

3. Pelab Exercise Ouestions: (22 points) CASE STUDY - the Pictet-Spengler Reaction! Tetrahydroisoquinolones can be synthesized in moderate yields from amines and carbonyl compounds in concentrated hydrochloric acid, as seen below. Based on this reaction answer the following questions: HCI + NH HH 100C NH 2 2-phenylethan formaldehyde 1.2.3.4-tetrahydro -1-amine isoquinoline BP 195C BP 235C 1. What would a silica TLC plate look like after this reaction has gone to -25, 50, 75, and 100% completion Indicate the relative locations (approximate Rvalues), and intensities of the spots (by shading) on the TLC plates below (4 points) 25% (15 min) 50% (30 min) 75% (45 min) 100% (60 min) Lane A Starting material 1 Lane B - Co-spot Lane Reaction mixture 60 points Chem 213W, Spring 2022 Distillation Prelab Assignment 84 b. Let's say we were monitoring this reaction by GC instead of TLC. Which compound would you expect to elute first? Second? Why? point) What would you expect a gas chromatogram to look like for each time point represented by the TLC plates on the previous page? Draw and label a rough GC chromatogram for each time point below (3 points) Runtime - 15 min Rxn time 30 min intensity intensity time Runtime - 45 min time Runtime - 60 min intensity intensity time time