Question: Are all assumptions stated? Were sensitivity analyses conducted for these assumptions? Many of the values used in pharmacoeconomic studies are based on assumptions. For example,

Are all assumptions stated? Were sensitivity analyses conducted for these assumptions? Many of the values used in pharmacoeconomic studies are based on assumptions. For example, authors may assume the adverse event rate is 5%, or that adherence with a regimen will be 80%. These types of assumptions should be stated explicitly. For important assumptions, was the estimate varied within a reasonable range of values? reference to Abhiroop Chakravarty, Mohini Rastogi, Praveen Dhankhar & Kelly F. Bell (2018): Comparison of costs and outcomes of dapagliflozin with other glucose-lowering therapy classes added to metformin using a short-term cost-effectiveness model in the US setting, Journal of Medical Economics, DOI: 10.1080/13696998.2018.1434182

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