Autoantibodies can cause different types of damage, including complement fixation and $$Press Space to openphagocytesinflammationantigenscell lysiscomplement$-$regulatory proteinsopsonization. Complement fixation causes $$Press Space to openphagocytesinflammationantigenscell lysiscomplement$-$regulatory proteinsopsonization, which kills the target cell, and $$Press Space to openphagocytesinflammationantigenscell lysiscomplement$-$regulatory proteinsopsonization, which recruits additional leukocytes. In autoimmune hemolytic anemia, red blood cells are killed through complement fixation and the uptake of $$Press Space to openphagocytesinflammationantigenscell lysiscomplement$-$regulatory proteinsopsonization. Red blood cells are particularly susceptible to these types of death because they have much lower levels of $$Press Space to openphagocytesinflammationantigenscell lysiscomplement$-$regulatory proteinsopsonization compared to nucleated cells.

phagocytes

inflammation

antigens

cell lysis

complement$-$regulatory proteins

opsonization