c. Binding: Stereochemistry When norepinephrine binds to the receptor, it takes full advantage of all the possible interactions (much like a hand in a glove or a key in a lock - it fits perfectly). Example 1 Which isomer of norepinephrine is binding to the B2-adrenergic receptor below? OH HO... SOH OH NH OH HIN. CH OH (99-norepinephrine (R)-norepinephrine Anne Ny Ser-OH Ser-OH Asp-0 B2-adrenergic receptor Example 2: Below is a cartoon of two enantiomers and how they interact with a receptor. Its enantiomer, structure B, is not able to take advantage of all the interactions. Structure A binding Structure B binding Is Structure A or Structure B bound more tightly? Circle one. Draw the Newman projection of Structure B rotated 60, 120, and 180 degrees. Is any conformation of Structure B able to take full advantage of all the possible binding pockets