$($c$)$

You are tasked with designing composite $3$D printed alginate$/$PCL scaffolds for a tissue engineering application $($Fig Q$1$c$).$ The compressive moduli of the alginate hydrogel and PCL polymer are $50$ kPa and $60$ MPa $,$ respectively.

i$.$ Estimate how much alginate and PCL should be included in the scaffold $($in relative terms$)$ to match native compressive modulus of articular cartilage $(2$ MPa $).$ State all assumptions you make for your estimation.

$[8]$

ii$.$ Based on your scaffold design, estimate how much strain chondrocytes embedded in the alginate bioink phase will experience under an applied stress of $0\mathrm{.}03$ MPa $.$

$[4]$