(c) Zinc (Zn) is an essential trace element for human, plants, animals and microorganisms. One of the Zn containing enzymes is carbonic anhydrase (CA). The CA catalyzes the reaction between carbon dioxide and water to form hydrogen carbonate at physiological condition, with acceleration of -107 relative to the uncatalyzed reaction. (i) Is Zn considered as a transition metal? Briefly explain your answer. (2 marks) (ii) Consider the mechanism of the carbonic anhydrase-mediated conversion of CO2 into HCO3- (Figure Q1C), briefly describe the role of Zn(II) in the active site. (8 marks) Carbonic Anhydrase (CA) CO2 (g) + H2O (1) HCO3- (aq) + H+ (aq), HCO3 OH H2O + Zn 'N N | 2n Zn N N N N SCO OH CO2 Zn IN N N Figure Q1C