Question: Can you explain how to answer this question? O COOH Drug-target Interactions NH 2 IZ Example 1: Methotrexate Glutam'is COOH HON residue Methotrexate Following entry

Can you explain how to answer this question?

O COOH Drug-target Interactions NH 2 IZ Example 1: Methotrexate Glutam'is COOH HON residue Methotrexate Following entry into the cell, methotrexate is activated by enzymes that add glutamic acid chains to one of the carboxylic acid moieties of methotrexate. This is an example of... a) Substrate mimicry x b) Phase I metabolism c) a prodrug strategy d) covalent inhibition inactivates Phase" would be added

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