Consider the two DNA sequences AGTCACG and AGACTG. We want to globally align them with the...
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Consider the two DNA sequences AGTCACG and AGACTG. We want to globally align them with the Needleman- Wunsch algorithm. First, we need to compute the optimal scoring matrix V shown below. Let the match cost be 3, mismatch= -1, and gap=-2. 1. Draw and fill up the scores table V using the Needleman-Wunsch recurrence (10 pts) v[i][j] = max { 2. Draw and fill up the traceback matrix. (8 pts) V[i-1] [j-1] + m(or mm) V[i-1] [j] + g V[i][j-1] + g 3. Write the final global alignment given by your traceback matrix. (7 pts) Activate Windows Consider the two DNA sequences AGTCACG and AGACTG. We want to globally align them with the Needleman- Wunsch algorithm. First, we need to compute the optimal scoring matrix V shown below. Let the match cost be 3, mismatch= -1, and gap=-2. 1. Draw and fill up the scores table V using the Needleman-Wunsch recurrence (10 pts) v[i][j] = max { 2. Draw and fill up the traceback matrix. (8 pts) V[i-1] [j-1] + m(or mm) V[i-1] [j] + g V[i][j-1] + g 3. Write the final global alignment given by your traceback matrix. (7 pts) Activate Windows
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Related Book For
Campbell Biology
ISBN: 978-0321775658
10th edition
Authors: Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson
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