When exposed to sodium hydroxide, Aspartame can undergo saponification. Draw the expected product of the reaction....
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When exposed to sodium hydroxide, Aspartame can undergo saponification. Draw the expected product of the reaction. Then, using pKa values for the 1 fully protonated forms of aspartic acid (pka's 1.9, 3.7, and 9.6) and phenyl alanine (pka's 1.8 and 9.1), estimate what the pH at which the new product formed will be neutral. pka (OH) = 2.9 HO By +H₂N pKa (NH3*) = 7.3 Aspartame OCH3 Saponification with NaOH When exposed to sodium hydroxide, Aspartame can undergo saponification. Draw the expected product of the reaction. Then, using pKa values for the 1 fully protonated forms of aspartic acid (pka's 1.9, 3.7, and 9.6) and phenyl alanine (pka's 1.8 and 9.1), estimate what the pH at which the new product formed will be neutral. pka (OH) = 2.9 HO By +H₂N pKa (NH3*) = 7.3 Aspartame OCH3 Saponification with NaOH
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