Question: Determine the pI for this synthesized pentapeptide: A-B-C-D-E Given that the pK values for the amino acids in the peptide are: Amino Acid pK 1

Determine the pI for this synthesized pentapeptide: A-B-C-D-E

Given that the pK values for the amino acids in the peptide are:

Amino Acid pK1 pK2 pKR
A 1.99 8.77
B 2.67 9.78 10.04
C 2.25 9.28
D 1.78 9.04 11.81
E 2.17 9.62

Give your answer to 2 places after the decimal.

Step by Step Solution

There are 3 Steps involved in it

1 Expert Approved Answer
Step: 1 Unlock blur-text-image
Question Has Been Solved by an Expert!

Get step-by-step solutions from verified subject matter experts

Step: 2 Unlock
Step: 3 Unlock

Students Have Also Explored These Related Mathematics Questions!

Q:

On December 31,2008, Crawford Resorts estimated that 1.5 percent of its net sales of $400,000 would become uncollectible. The company recorded this amount as an addition to Allowance for Doubtful...

Q:

Given the peptide: R-K-G-C-V a. Complete name of the pentapeptide b. Draw the structure of the pentapeptide at pH=9 and pH=11 c. Calculate the pI of the peptide. Refer to Table of pK values of...

Q:

1.) Given the peptide : K-R-G-V-C a. Complete name of the pentapeptide. b. Draw the structure of the pentapeptide at pH=9 and pH=11. c. Calculate the pI of the peptide. Refer to Table of pK values of...

Q:

Show how the pI values for the amino acids in Problem 32 (see Table 26-1) are derived. For each amino acid that possesses more than two pK a values, give the reason for your choice when calculating...

Q:

PROBLEM SET 1 AMIVO ACIDS AND PF.PTIDE.S 1. Suggest a reason why amino acids are usually more soluble at pH extremes than they are at neutral pH. (Note: This does not mean that they are insoluble at...

Q:

pleas the goals and techniques in details CHEM 2710L Experiment 3: Ionic Properties of Amino Acids Name: Partner Name: Date Lab Performed: 2023-01-31. Introduction What was/were the overall goal(s)...

Q:

Isoelectric focusing can separate peptides based on their relative contents of acidic and basic residues. When voltage is applied to an electrophoretic gel with a pH gradient, each peptide migrates...

Q:

1. (12 points) Consider the oligopeptide given below (written in the 3-letter code): Thr-Cys-Lys-Val-Tyr-Asn . Draw its full chemical structure as it would exist at pH = 7.0. Draw an arrow pointing...

Q:

Prepare a titration plot for the amino acid titration. From the graph determine whether your acid is mono-, di-, or triprotic, determine its pK, value(s), and its formula weight. Use dashed lines on...

Q:

Hint Check Answer [ Give Up? Resources KY 75.5% Assignment Score: Attempt 2 Isoclectric focusing can separate peptides based on their relative contents of acidic and basic residues. When voltage is...

Q:

In addition to the conventional 20 amino acids in Tables 26-1 and 26-3, two others, selenocysteine (Sec) and pyrrolysine (Pyl), are incorporated into proteins using the nucleic acidbased cell...

Q:

Consider the following game tree representing a simple dollar auction game. The following describes the extensive-form game in detail. THE PLAYERS: Bidders 1 and 2, each with a wealth level of $3....

Q:

If the Taylor polynomial of order 3 generated by the function 26 f(x) = 2V at a = 2 is P;(1) = A+ B(x 2) + C(x 2) + D(x 2) then C +D = 29 29 19 19

Q:

Revenues recelved from providing services are referred to as a . net income. b . nonrecurring income. c . fees earned. d . sales.

Q:

the mean weight among a group of female high school seniors is 120 lbs., with a standard deviation of 16.49 lbs. Assuming a normal distribution, find the percentiles for the following weight scores....