• Discuss the alignments, can the sequence difference between the white and red coding sequences be attributed to the difference in the base sequence of ADE1. 
• Identify the type of mutation present in the coding sequence and discuss the implications of the protein.
• DNA sequence numbered 60 to 903 (picture 1)n
  Protein sequence numbered 60 to 299 (picture 2)n
  White coding sequence: White Yeast n
  Red coding sequence: red yeast n
  n
  ADE1: genen
  n
  Dash marks in the sequence represent deletion or mutation.  n
  n
  Nucleotide and protein changes from comparisons of white and red ADE1

Transcribed Image Text:

WhitecodingADE1 RedcodingADE1 ATGTCAATTACGAAGACTGAACTGGACGGTATATTGCCATTGGTGGCCAGAGGIAAAGTT 60 ATGTCAATTACGAAGACTGAACTGGACGGEATAT TTGGTGGCCAGAGGTAAAGET 60 ***** 120 WhitecodingADE1 RedcodingADE1 AGAGACATATATGAGGTAGACGCTGGTACGT TCGTATCTCT AGAGACATATATGAGGTAGACGCTGGTACGTTGCZGTTGTTGCTACGGATCCTATCTCT 120 WаitecodingADв1 RedcodingADE1 GCATATGACGTTATTATGGAA CTATTGACCAAACra 180 GCATATGACGTTATTATGGAAAACAGCA cerGAAAAGGGGATCCTATTGACCAAACTG 180 NаitecodingADв1 RedcodingADE1 TCAGAGTTCTGGTTCAAGTTCCTGTo ATGITC TTTGGTCGACATCGcC 240 TCAGAGTTCTGGTICAAGITCCTGTcc .CGATGTTCGT ATCATITGGTCGACATCace 240 ...... WhitecodingADE1 RedcodingADE1 CCAGGIAAGACTATTTTCGATTATCTACCTSCAAAATTGAGCGAACCAAAGTACAAAACG 300 CCAGGIAAGACTATTTTCGATTATCTACCTGCAAAATTGAGCGAACCAAAGTACAAAACG 300 WhitecodingADE1 RedcodingADE1 CAACTAGAAGACCGCTCTCTATTGGTICACAAACATAAACTAATTCCATTGGAAGTAATT 360 CAACTAGAAGACCGCTCTCTATTGGTICACAAACATAAACTAATTCCATTGGAAGTAATT *************** 360 NаitecodingADв1 RedcodingADE1 GTCAGAGGCTACATCACCGGATCTGCTTGGAAAGAGTACCTAAAAACAGGTACTSTGCAT 420 GTCAGAGGCTACATCACCGGATCTGerrGGAAAGAGTACCTAAAAACAGGTCTSTGCAT 420 WhitecodingADE1 RedcodingADE1 GGTTTGAAACAACCTCAAGGACTTAAAGAATCTCAAGAGTTCCCAGACCAATCTTCACC 480 GGTTTGAAACAACCTCAAGGACTTAAAGAATCTCAAGAGTTCCCAGAACCAATCTTCACc 480 WhitecodingADE1 RedcodingADE1 CCATCGACCAAGGCTGAACAAGGTGAACATGA ссссст 540 CATCGACCAAGGCTGAACAAGGTGAACATGACGAA тстсстессслсссссст 540 WhitecodingADE1 RedcodingADE1 GAGCTGGTGGGTGAAGATTTGICACGTAGAGTGGCAGAACTGGCTGTAAAACTGTACTCC 600 GAGCTGGTGGGTGAAGATTTGICACGTAGAGTGGCAGAACTGGCTGTAAAACTGTACTCC 600 WhitecodingADE1 RedcodingADE1 AAGTGCAAAGATTATGCTAAGGAGAGGGCATCAT ATCGCAGACACTAAATTCGAATTC 660 AAGTGCAAAGATTATGCTAAGGAGAAGGGCATCATCATCCCAGACACTAAATTCGAATTc 660 ****. WhitecodingADE1 RedcodingADE1 GGTATTGACGAAAAGACCAATGAAATTATTCTAGIGGACGAGGTGCTAACGCCAGACTCC 720 GGTATTGACGAAAGACCAATGAAATTATTCTAGIGGACGAGGTGCTAACGCCAGACTCc 720 ******* **** WаitecodingADв1 RedcodingADE1 TCTAGATTCTGGAACGGTGCCTCTTATAAGGTAGGAGAATCCCAAGATTCTTACGATAAG 780 TCTAGATTCTGGAACGGTGCCTCTTATAAGGTAGGAGAATCCCAAGATTCITACGATAAG 780 WhitecodingADE1 RedcodingADE1 CAATTITTAAGAGACTGGCTTACTGCTAATAAGTIGAACGGTGTTAACGGCGT-CAMAAT 839 CAATTITTAAGAGACTGGCCTACTGCTAATAAGTTGAACGGTGTTAGACGGCCTCAAAAT 840 ... ****.. WhitecodingADE1 RedcodingADE1 GCCCCAAGACATTGTCGACAGGACAAGGGCCAAATATATAGAGGCITATGAAACATTGAC 899 GCCCCAAGACATTGTCGACAAAAAAGGGC-CATATATATGGGGC-CCATGAAACATTGAT 898 ************ **** ******** .. ************ WhitecodingADE1 RedcodingADE1 AGGGTCTAAATGGICTCACTAA 921 AGAAA- 903 .. WhitecodingADE1 RedcodingADE1 ATGTCAATTACGAAGACTGAACTGGACGGTATATTGCCATTGGTGGCCAGAGGIAAAGTT 60 ATGTCAATTACGAAGACTGAACTGGACGGEATAT TTGGTGGCCAGAGGTAAAGET 60 ***** 120 WhitecodingADE1 RedcodingADE1 AGAGACATATATGAGGTAGACGCTGGTACGT TCGTATCTCT AGAGACATATATGAGGTAGACGCTGGTACGTTGCZGTTGTTGCTACGGATCCTATCTCT 120 WаitecodingADв1 RedcodingADE1 GCATATGACGTTATTATGGAA CTATTGACCAAACra 180 GCATATGACGTTATTATGGAAAACAGCA cerGAAAAGGGGATCCTATTGACCAAACTG 180 NаitecodingADв1 RedcodingADE1 TCAGAGTTCTGGTTCAAGTTCCTGTo ATGITC TTTGGTCGACATCGcC 240 TCAGAGTTCTGGTICAAGITCCTGTcc .CGATGTTCGT ATCATITGGTCGACATCace 240 ...... WhitecodingADE1 RedcodingADE1 CCAGGIAAGACTATTTTCGATTATCTACCTSCAAAATTGAGCGAACCAAAGTACAAAACG 300 CCAGGIAAGACTATTTTCGATTATCTACCTGCAAAATTGAGCGAACCAAAGTACAAAACG 300 WhitecodingADE1 RedcodingADE1 CAACTAGAAGACCGCTCTCTATTGGTICACAAACATAAACTAATTCCATTGGAAGTAATT 360 CAACTAGAAGACCGCTCTCTATTGGTICACAAACATAAACTAATTCCATTGGAAGTAATT *************** 360 NаitecodingADв1 RedcodingADE1 GTCAGAGGCTACATCACCGGATCTGCTTGGAAAGAGTACCTAAAAACAGGTACTSTGCAT 420 GTCAGAGGCTACATCACCGGATCTGerrGGAAAGAGTACCTAAAAACAGGTCTSTGCAT 420 WhitecodingADE1 RedcodingADE1 GGTTTGAAACAACCTCAAGGACTTAAAGAATCTCAAGAGTTCCCAGACCAATCTTCACC 480 GGTTTGAAACAACCTCAAGGACTTAAAGAATCTCAAGAGTTCCCAGAACCAATCTTCACc 480 WhitecodingADE1 RedcodingADE1 CCATCGACCAAGGCTGAACAAGGTGAACATGA ссссст 540 CATCGACCAAGGCTGAACAAGGTGAACATGACGAA тстсстессслсссссст 540 WhitecodingADE1 RedcodingADE1 GAGCTGGTGGGTGAAGATTTGICACGTAGAGTGGCAGAACTGGCTGTAAAACTGTACTCC 600 GAGCTGGTGGGTGAAGATTTGICACGTAGAGTGGCAGAACTGGCTGTAAAACTGTACTCC 600 WhitecodingADE1 RedcodingADE1 AAGTGCAAAGATTATGCTAAGGAGAGGGCATCAT ATCGCAGACACTAAATTCGAATTC 660 AAGTGCAAAGATTATGCTAAGGAGAAGGGCATCATCATCCCAGACACTAAATTCGAATTc 660 ****. WhitecodingADE1 RedcodingADE1 GGTATTGACGAAAAGACCAATGAAATTATTCTAGIGGACGAGGTGCTAACGCCAGACTCC 720 GGTATTGACGAAAGACCAATGAAATTATTCTAGIGGACGAGGTGCTAACGCCAGACTCc 720 ******* **** WаitecodingADв1 RedcodingADE1 TCTAGATTCTGGAACGGTGCCTCTTATAAGGTAGGAGAATCCCAAGATTCTTACGATAAG 780 TCTAGATTCTGGAACGGTGCCTCTTATAAGGTAGGAGAATCCCAAGATTCITACGATAAG 780 WhitecodingADE1 RedcodingADE1 CAATTITTAAGAGACTGGCTTACTGCTAATAAGTIGAACGGTGTTAACGGCGT-CAMAAT 839 CAATTITTAAGAGACTGGCCTACTGCTAATAAGTTGAACGGTGTTAGACGGCCTCAAAAT 840 ... ****.. WhitecodingADE1 RedcodingADE1 GCCCCAAGACATTGTCGACAGGACAAGGGCCAAATATATAGAGGCITATGAAACATTGAC 899 GCCCCAAGACATTGTCGACAAAAAAGGGC-CATATATATGGGGC-CCATGAAACATTGAT 898 ************ **** ******** .. ************ WhitecodingADE1 RedcodingADE1 AGGGTCTAAATGGICTCACTAA 921 AGAAA- 903 ..

Answer rating: 100% (QA)

ADE1 ADE1 is a gene in Saccharomyces cerevisae that codes for Phosphoribosylaminoimidazolesuccinocar... View the full answer