Draw a chemical diagram of BPG bound in the deoxy state of hemoglobin showing the specific ionic interactions with sidechains and functional groups. The structure of BPG and sidechains and key contacts must be drawn in detail. Acid chlorides react with amino groups to yield amides. The compound to the right was made and evaluated as a drug to modify O2 transport by hemoglobin. Predict the effect this compound would have on O2 affinity, H+ transport, and CO2 transport. Draw a chemical diagram of the drug interaction with hemoglobin to explain your theories.

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CI O. P- CI O. P-