Question: Example 1: During the formulation of a solid oral dosage form, a blending process was optimized at a pilot plant scale up using a 200L

Example 1: During the formulation of a solid oral dosage form, a blending process was optimized at a pilot plant scale up using a 200L Bin blender. The 200L blender was operated for 15rpm for 20 min to obtain the desired blend uniformity. Calculate the operating parameters, if the blending process was scaled up from 200L to 1500L Bin blender. Assume we have to operate 1500L at 12rpm as the machine is qualified in 8-12 rpm range

Step by Step Solution

There are 3 Steps involved in it

1 Expert Approved Answer

Step: 1 Unlock blur-text-image

Question Has Been Solved by an Expert!

Get step-by-step solutions from verified subject matter experts

Step: 2 Unlock

Step: 3 Unlock

Students Have Also Explored These Related General Management Questions!

Find attached Ingredients: Water, MCC, Salt, Nicotine, pH regulator, sweeteners and flavours I am wondering why the decision to go with LYFT. I understand migrating to LYFT would be easier from sells...

Nucleon 1) Describe the vertical chain for biotechnology productions. What "make" decisions has Nucleon already made? What "buy" decisions has it already made? Evaluate these decisions. 2) Draw a...

chegg.com/homework-help/questions-and-answers/1-describe-vertical-chain-biotechnology-productions-make The CRP-1 Project: Current Applications Since Nucleon's founding, its main development project...

37.2021 X C 1) Describe The Vertical Chain Fo x Study.com - Search for courses, I x +...

Using the case study listed below, I need help with the following question Which option do you think management should take and provide justification? Think about this as you have two stages of...

The Pharmaceutical Industry: An Industry Note The pharmaceutical industry consisted of all enterprises that were involved in the invention of drugs, production of the active substances in drugs,...

m BD 1/24 PROJECT MUSE Indigenous Circuits: Navajo Women and the Racialization of Early Electronic Manufacture Lisa Nakamura American Quarterly, Volume 66, Number 4, December 2014, pp. 919-941...

Answer the following questions according to the case (Supply Chain Management in STARBUCKS and its Impact on Company Performance) provided below the asked questions: What are the main issues that...

. Problem 6. A number of boys and a number of girls will attend a ballroom dancing party. The rule is that only a boy and a girl can dance together, and the pair is fixed for the whole party (i.e. if...

Good Morning, This is the 3rd homework assignment I am requesting of you as you have did excellent on the two prior which I greatly appreciate. This is a new course that is starting today and I am...

Two species of singly charged positive ions of masses 20.0 x 1027 kg and 23.4 x 1027 kg enter a magnetic field at the same location with a speed of 1.00 x 105 m/s. If the strength of the field is...

Why is a reputation for honesty and fair business practice important to the financial value of the corporation?

ACC 551 Novak Corporation purchased for $ 3 1 1 , 0 0 0 a 2 5 % interest in Murphy, Inc. This investment enables Novak to exert significant influence over Murphy. During the year, Murphy earned net...

The value of international accounting standards has been discussed for a number of years, but with the increased global activity in business in recent history, the need for such has grown in...