Question: Food can both increase and decrease bioavailability. Below are given several scenarios for food effect. Indicat which situations may INCREASE or DECREASE the bioavailability of

Food can both increase and decrease bioavailability. Below are given several

Food can both increase and decrease bioavailability. Below are given several scenarios for food effect. Indicat which situations may INCREASE or DECREASE the bioavailability of drugs. Explain your rational 1. Food with high fat content together with a lipophilic, low solubility drug. 2. A meal that slows the gastric emptying for a drug that is actively absorbed 3. Food that contains organic acids together with drugs absorbed by organic cation transporters 4. Food with high fat content together with drugs that are substrates for the PGP transporter 5. Food that interact with the PGP transporter together with drugs that are substrates for the PGP transporter

Step by Step Solution

There are 3 Steps involved in it

1 Expert Approved Answer

Step: 1 Unlock blur-text-image

Question Has Been Solved by an Expert!

Get step-by-step solutions from verified subject matter experts

Step: 2 Unlock

Step: 3 Unlock

Students Have Also Explored These Related Chemical Engineering Questions!

Hello, I havetwo articles about S Corp. and C Corp., and IJUST need towrite a conclusion paragraph based on professor's questions. can you help me to write it? Articles are attached Accounting...

4 Files 12:47 PM Mon May 16 Insert Draw Layout Review View Unit 3Microec0nomics Name: ELASTICITY Use the space below to take notes during class. Elastic: Unit Elastic: Inelastic: Perfect...

Group Presentation Christus Spohn I. II. III. IV. Outline Problem a. Effective Staffing Under Numerous Constraints i. Short Staffing 1. Have too much staff/don't have enough staff 2. Work standard...

seventh pages Chapter 3 Curve Sketching How much metal would be required to make a 400-mL soup can? What is the least amount of cardboard needed to build a box that holds 3000 cm3 of cereal? The...

To be solved by DKetan. Using Chapter 7 of your text as a reference, define a standard cost and explain what constitutes the components of a standard cost. Describe the advantages and disadvantages...

Montonya Company has the following selected data for the current year: Sales (10,000 units) $90,000 Direct materials 30,000 Direct labor costs 10,000 Variable manufacturing overhead 3,500 Fixed...

Files 12:56 PM Mon May 16 25% Unit+2+workbook Q . . . Home Insert Draw Layout Review View Calibri Bold (Body) 36 B I U aAv A v Unit 2-Supply and Demand Name: HR: LAW OF SUPPLY Use the space below to...

Montonya Company has the following selected data for the current year: Sales (10,000 units) $90,000 Direct materials 30,000 Direct labor costs 10,000 Variable manufacturing overhead 3,500 Fixed...

Business Research MethodologyQuestion Bank 1 1. When the marketing department of an organization attempts to determine the amount of time the managers in this department spend at their computers in...

Marcy transferred $40,000 into a trust two years ago. She named her bank as trustee, her husband Marshall as the income beneficiary, and their children Russ and Audrey as the remainder beneficiaries....

Interactive 3D display mode H H,C-C-C-N-H H, H, Spell out the full name of the compound.

Questlon 1 7 ( 9 points ) On January 1 . Year 1 . Lacrosse Corp granted Corky, its president, 1 0 , 0 0 0 stock appreciation rights ( SARs ) . Upon exercise, Corky may choose to receive cash for the...

Consider the language L = {wcw R : w {d, e}*}, where w R denotes the reversal of the string w (such that for example (abc) R = cba). Give a context-free grammar that generates L.

6. The following example is taken from a small technical consulting company that specializes in providing highly qualified technical consultants to the oil industry.

Focuses strongly on achievement and success in self and others.

Inspires enthusiasm and energy in others to follow a given direction.