For genomic sequencing, a map$-$based method while a whole$-$genome shotgun approach.

$q,$

$$

requires no prior knowledge of the genome; requires detailed genetic and physical maps maps to order the overlapping clones

uses genetic$/$physical maps to order sequenced fragments; uses overlap in sequence to order sequenced fragments

was used to sequence the human genome; was developed much more recently and was therefore not used to sequence the human genome

was never employed for producing the final human genome sequence; was used to sequence the human genome