A clinical trial for a drug to help with chronic headaches had 1062 patients who were...
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A clinical trial for a drug to help with chronic headaches had 1062 patients who were put either into a treatment group (521) or a placebo group (541). The estimated proportion of patients who reported improvement in symptoms after taking the drug or placebo for 6 months was 6.7% in the placebo group and 11.9% in the treatment group. Our purpose here is to see if the proportion of patients with improvement differs significantly between the two groups. (a) What is the parameter of interest in this study? (b) Let purt be the proportion of patients with symptom improvement in the treatment group and let Pplacebo be the proportion of patients with symptom improvement in the placebo group. Calculate a 90% confidence interval for ptrt - Pplacebo. Give your answer to 2 sig. fig. (c) Now calculate a 90% confidence interval for Pplacebo - Ptrt. What stays the same and what changes from what you obtained in part (b)? (d) Based on the results, are the researchers able to state with 90% confidence that there is a difference in the estimated proportion of those who will experience symptom improvement between the placebo and the treatment groups. A clinical trial for a drug to help with chronic headaches had 1062 patients who were put either into a treatment group (521) or a placebo group (541). The estimated proportion of patients who reported improvement in symptoms after taking the drug or placebo for 6 months was 6.7% in the placebo group and 11.9% in the treatment group. Our purpose here is to see if the proportion of patients with improvement differs significantly between the two groups. (a) What is the parameter of interest in this study? (b) Let purt be the proportion of patients with symptom improvement in the treatment group and let Pplacebo be the proportion of patients with symptom improvement in the placebo group. Calculate a 90% confidence interval for ptrt - Pplacebo. Give your answer to 2 sig. fig. (c) Now calculate a 90% confidence interval for Pplacebo - Ptrt. What stays the same and what changes from what you obtained in part (b)? (d) Based on the results, are the researchers able to state with 90% confidence that there is a difference in the estimated proportion of those who will experience symptom improvement between the placebo and the treatment groups.
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Related Book For
OM operations management
ISBN: 978-1285451374
5th edition
Authors: David Alan Collier, James R. Evans
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