Glycogen Phosphorylase Equilibrium Glycogen phosphorylase catalyzes the removal of glucose from glycogen. The AG for this...
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Glycogen Phosphorylase Equilibrium Glycogen phosphorylase catalyzes the removal of glucose from glycogen. The AG" for this reaction is 3.1 kJ/mol. (a) Calculate the ratio of [P] to [glucose 1-phosphate] when the reaction is at equilibrium. (Hint: The removal of glucose units from glycogen does not change the glycogen concentration.) (b) The measured ratio [P://Iglucose 1-phosphate] in myocytes under physiological conditions is more than 100:1. What does this indicate about the direction of metabolite flow through the glycogen phosphorylase reaction in muscle? (e) Why are the equilibrium and physiological ratios different? What is the possible significance of this difference? Glycogen Phosphorylase Equilibrium Glycogen phosphorylase catalyzes the removal of glucose from glycogen. The AG" for this reaction is 3.1 kJ/mol. (a) Calculate the ratio of [P] to [glucose 1-phosphate] when the reaction is at equilibrium. (Hint: The removal of glucose units from glycogen does not change the glycogen concentration.) (b) The measured ratio [P://Iglucose 1-phosphate] in myocytes under physiological conditions is more than 100:1. What does this indicate about the direction of metabolite flow through the glycogen phosphorylase reaction in muscle? (e) Why are the equilibrium and physiological ratios different? What is the possible significance of this difference?
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Related Book For
Fundamentals of biochemistry Life at the Molecular Level
ISBN: 978-0470547847
4th edition
Authors: Donald Voet, Judith G. Voet, Charlotte W. Pratt
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