Question: How do non-coding RNAs, such as microRNAs and long non-coding RNAs, participate in gene regulation and cellular homeostasis, and what therapeutic strategies can be devised

How do non-coding RNAs, such as microRNAs and long non-coding RNAs, participate in gene regulation and cellular homeostasis, and what therapeutic strategies can be devised to modulate their activity in disease states?

Step by Step Solution

★★★★★

3.49 Rating (149 Votes )

There are 3 Steps involved in it

1 Expert Approved Answer

Step: 1 Unlock

NonCoding RNAs ncRNAs in Gene Regulation and Cellular Homeostasis MicroRNAs miRNAs Function miRNAs are short about 22 nucleotides noncoding RNA molecules that play a crucial role in posttranscriptiona... View full answer

Question Has Been Solved by an Expert!

Get step-by-step solutions from verified subject matter experts

Step: 2 Unlock

Step: 3 Unlock

Students Have Also Explored These Related Biology Questions!

What is the role of non-coding RNAs, such as microRNAs and long non-coding RNAs, in post-transcriptional regulation of gene expression, and how do they contribute to disease pathogenesis?"

What is the role of non-coding RNAs, such as microRNAs and long non-coding RNAs, in post-transcriptional gene regulation, and how do dysregulations in their expression contribute to the pathogenesis...

What is the significance of DNA supercoiling in molecular biology, and how does it affect DNA structure and function? Explain the concept of DNA methylation and its role in epigenetics. How does it...

Evaluate the role of non-coding RNAs, such as microRNAs and long non-coding RNAs, in post-transcriptional gene regulation, cellular differentiation, and disease pathogenesis, highlighting their...

Could you elaborate on the role of non-coding RNAs, such as microRNAs and long non-coding RNAs, in post-transcriptional gene regulation, and their implications in various biological processes...

Analyze the role of non-coding RNAs, such as microRNAs and long non-coding RNAs, in post-transcriptional gene regulation and their implications in human health and disease .

discuss the role of non-coding RNAs, such as microRNAs, long non-coding RNAs, and small interfering RNAs, in post-transcriptional gene regulation, chromatin remodeling, and epigenetic silencing, and...

How do non-coding RNAs, such as long non-coding RNAs and microRNAs, participate in chromosomal organization and gene regulation, and what are their functional roles in chromatin remodeling and...

What role do non-coding RNAs, including microRNAs and long non-coding RNAs, play in regulating cellular processes and genetic pathways ?

Can you explain the role of non-coding RNAs, including microRNAs and long non-coding RNAs, in post-transcriptional gene regulation and their potential as therapeutic targets for various diseases?

Danny Steele owns a small specialty store, named Steeles Storeroom, whose year-end is June 30. Determine the total amount that should be included in Steeles Storerooms year-end inventory. A physical...

You have been asked to determine the effect of per capita disposable income on retail sales using cross-section data by state. The data are contained in the data file Economic Activity. Estimate the...

Evaluate the definite integral exactly. 1 4 . 5 7 x - 1 d x

Fill in the consolidation working paper as necessary to consolidate Piaget and Schenks balance sheet accounts at the date of acquisition. Use this information for the following 5 questions. What is...

Draw a bpm model of the following. (DO NOT DESCRIBE IT, JUST STEP BY STEP MODEL) An order handling process starts when an order is received. The order is first registered. If the current date is not...

Ethical Dilemma - Case Study Rita returned to work after a period off for maternity leave and is now employed at a neighborhood medical office part-time as an accountant. She reports to a practice...

Write a general expression using letters to abstract a general form from the given set of numerical data. a. 23 = 3 + 3 25 = 5 + 5 214 = 14 + 14 227 = 27 + 27 b. 23 + 25 = 28 712 + 78 = 720 540 + 52...

4. Testing Services Inc. is expected to have earnings of $6 per share this com- ing year. It expects earning will grow at 15% for three years. The company projects that from the third year (time 3)...

The return of goods to the supplier will affect the purchase account. Question 27Answer True False

What biochemical reaction is catalyzed by -secretase? Why was it proposed that a chemical inhibitor of this activity might be a useful drug for treating Alzheimer's disease? What possible side...

The TGN, trans-Golgi network, is the site of multiple sorting processes as proteins and lipids exit the Golgi complex. Compare and contrast the sorting of proteins to lysosomes versus the packaging...

True or False: Since ATP is generated in chloroplasts, cells capable of undergoing photosynthesis do not require mitochondria. Explain. Name and describe the idea that explains how mitochondria and...

Vale S.A., a Brazilian mineral products company, provided the following note on a voluntary basis in its 2009 annual report: 11Cash Generation (Unaudited) Consolidated operating cash generation...

Refer to the worksheets in Exhibits 10.12 and 10.13 in which the financial statements of Arcot Company have been restated to U.S. GAAP. Required: a. Calculate each of the ratios listed below using...

Refer to the following information provided in the chapter for Arcot Company: Consolidated financial statements in Exhibits 10.8 and 10.9. Differences between Local GAAP and U.S. GAAP in Exhibit...