Question: How does the transmission bottleneck impact Mtb evolution? Reduces the effective population size, making natural selection less efficient and random genetic drift is increased. Increases

How does the transmission bottleneck impact Mtb evolution?
Reduces the effective population size, making natural selection less efficient and random genetic drift is increased.
Increases purifying selection and simultaneously increases the effective population size.
Increases the effective population size, making natural selection more efficient and random genetic drift is decreased.
Reduces natural selection by reducing random genetic drift and increasing the purifying selection.
How does the transmission bottleneck impact Mtb

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