Huntington disease (HD) is a rare autosomal dominant condition in humans that results in a slow...

Transcribed Image Text:

Huntington disease (HD) is a rare autosomal dominant condition in humans that results in a slow but inexorable deterioration of the nervous system. HD shows age-dependent penetrance, which is to say that the probability that a person with HD genotype will express the phenotype varies with age. Assume that 50% of those inheriting the HD allele will express the symptoms by age 40. Susan is a 35 year old woman whose father has HD. She currently shows no symptoms. What is the probability that Susan will show the symptoms in five years? Express your answer as a decimal, e.g., if you think she has a 3/4 chance (75 % chance ) , write your answer as O.75. Huntington disease (HD) is a rare autosomal dominant condition in humans that results in a slow but inexorable deterioration of the nervous system. HD shows age-dependent penetrance, which is to say that the probability that a person with HD genotype will express the phenotype varies with age. Assume that 50% of those inheriting the HD allele will express the symptoms by age 40. Susan is a 35 year old woman whose father has HD. She currently shows no symptoms. What is the probability that Susan will show the symptoms in five years? Express your answer as a decimal, e.g., if you think she has a 3/4 chance (75 % chance ) , write your answer as O.75.

Answer rating: 100% (QA)

For Autosomal Dominant diseased we Know that 1Both sex eq... View the full answer