Question: Hypothetical example. You have received a new molecule where someone tried to develop a liquid formulation, but was not able to provide adequate stability. Their

Hypothetical example. You have received a new molecule where someone tried to develop a liquid formulation, but was not able to provide adequate stability. Their best formulation contained 20 mg/mL protein (5%) in 20 mM histidine (0.3%), 85 mM NaCl (0.5%), 3% sorbitol, pH 6.0.

What is the glass transition temperature of this formulation (assume Tg' of protein is -10 C, sodium chloride is -120 C). Only enter the number (to one decimal place) in degrees C (exclude the units).

Step by Step Solution

There are 3 Steps involved in it

1 Expert Approved Answer

Step: 1 Unlock blur-text-image

Question Has Been Solved by an Expert!

Get step-by-step solutions from verified subject matter experts

Step: 2 Unlock

Step: 3 Unlock

Students Have Also Explored These Related Chemical Engineering Questions!

Reconsider the example of choosing the advertising budget for the VRX2000 that is presented in Section 1.4. There it was determined that the optimal level of advertising spending was $135,392 leading...

Hypothetical example ( will repeat for remaining problems You have received a new molecule where someone tried to develop a liquid formulation but was not able to provide adequate stability. Their...

Hypothetical example (will repeat for remaining problems You have received a new molecule where someone tried to develop a liquid formulation but was not able to provide adequate stability. Their...

Budgeting for Nonprofit Organizations Although budgeting is just as important for nonprofit organizations as for for-profit companies, the approach taken toward budgeting can be very different. In...

identify an adult entertainment district in a city of your choice. Explain about how you identify and apply Cameron (2004)'s Typology of Sex Economies to describe the district. Urban Studies, Vol....

(Questions from Lecture and Article) - Discussion Board Activity I need to read the following Lecture Note and the ?Wall Street Journal? articles that I uploaded, and writeanswers for theDiscussion...

Calculate these numbers for 2010 Annual Report Net Income Preferred Dividends Average Common shares outstanding Stock price per share Earnings per share Gross profit Net Sales Average total assets...

Please complete the assignment and t explain all the ratios that was use and effect. Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549...

Write a bhaskara function that receives the values of a, b, and c and returns x1 and x2. To return multiple values from a function, you can use a data structure like a list as follows return [x1,...

Nine percent of men and 0.25% of women cannot distinguish between the colours red and green. This is the type of colour blindness that causes problems with traffic signals. If 6 men are randomly...

Amounts recelved that will be returned or remitted to others at a fuhure date are recognized as: Iabilities assets expenses losses

An investor wishes to use the Capital Asset Pricing Model to calculate the required rate of return. If the risk free rate is 1.05%, the market rate is 9%, and beta is 1.35 . Calcuate the required...

Read the Alberga (1997) article on IiP, then talk to two people who have had experience as employees of IiP and compare their views of the effectiveness of the accreditation

Identify the benefi ts to management of introducing coaching and/or mentoring into your organisation.

Debate the viewpoint that cyber- harassment and bullying can be just as demeaning as conventional bullying but may not receive the same degree of sympathy from witnesses.