i. Consider the following ring systems 1-4. 

List the properties that are needed for a molecule to be aromatic. Comment briefly about each and indicate clearly (with reasons) whether or not it should be aromatic? 4 marks 

ii. 4-Amino-N-(5-methylisoxazol-3-yl)-benzenesulfonamide) is an antibiotic with the trade name sulfamethoxazole. It was recently depicted as having the structure 5. 

• By considerations of aromaticity and charge explain why this structure must be wrong. 3 marks 

• Give the correct structure for the molecule. 1 mark

Transcribed Image Text:

N. CIO, 1 4 I-Z 2. N. CIO, 1 4 I-Z 2.

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The necessary conditions for a compound to show aromaticity are as follows 1 The molecule must be pl... View the full answer