I need help please. one-compartment first-order absorption homework.

show steps please.

2. Drug quastification trom plasma is comenoty performed by using techniques such as HPLC or LCMS. However, these methodr do have limitations, and investigators may choose to ure a ratiolabeled analog of a drug instead. Radioligands are molecules that coetain radioactive isotopes, commeoly if or 14C. This technique allows investigatoen to quantify drug concentration from radiation measurements. The following measurements were made in 2508. tats followaing ofal adminiatration of 182 Ci of a 14C-labeled drug of interest: Note that a Ci is a measure of the amount of radioactivity and hence is a measure of the amount of drug present. Given that the oral bioavailability of this drug is known to be essentially 100%, estimate the following from this data: ( 5 points per variable; total of 30 points for parts a-f) (a) elimination rate constant, k (b) elimination half-life, ti/2,elim (c) absorption rate constant, ka (d) absorption half-life, ti/2,abs (e) volume of distribution, V (f) clearance, CL 2. Drug quastification trom plasma is comenoty performed by using techniques such as HPLC or LCMS. However, these methodr do have limitations, and investigators may choose to ure a ratiolabeled analog of a drug instead. Radioligands are molecules that coetain radioactive isotopes, commeoly if or 14C. This technique allows investigatoen to quantify drug concentration from radiation measurements. The following measurements were made in 2508. tats followaing ofal adminiatration of 182 Ci of a 14C-labeled drug of interest: Note that a Ci is a measure of the amount of radioactivity and hence is a measure of the amount of drug present. Given that the oral bioavailability of this drug is known to be essentially 100%, estimate the following from this data: ( 5 points per variable; total of 30 points for parts a-f) (a) elimination rate constant, k (b) elimination half-life, ti/2,elim (c) absorption rate constant, ka (d) absorption half-life, ti/2,abs (e) volume of distribution, V (f) clearance, CL