Question: In its active GTP - bound form, the small G protein Ras binds to the serine / threonine kinase Raf 1 , thereby recruiting Raf
In its active GTPbound form, the small G protein Ras binds to the serinethreonine kinase Raf thereby recruiting Raf to the plasma membrane and inducing Raf activation. T cells that lack expression of RasGAP proteins spontaneously develop into Tcell leukemias. What would these cells show?
an absence of GDPbound Rasincreased levels of activated Rafreduced levels of Raf at the plasma membrane
increased levels of Ras bound to RasGEFsreduced levels of GTPbound Ras
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