Question: In some enzyme - catalyzed reactions, multiple complexes are involved as follows: E + S k 1 ? k 2 E S ( E S

In some enzyme-catalyzed reactions, multiple complexes are involved as follows:
E+Sk1?k2ES
(ES)1k4k3(ES)2
(ES)2k5E+P
Develop a rate expression using
(a) the Michaelis-Menten approach and
(b) the Briggs-Haldane approach.
 In some enzyme-catalyzed reactions, multiple complexes are involved as follows: E+Sk1?k2ES

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