Integrated Problem 07.92d Get help answering Molecular Drawing questions. x Incorrect. Identify the chiral centers adjacent to the ester groups. Pladienolide B is a macrocyclic (large-ring) natural product isolated from an engineered strain of the bacterium Streptomyces platensis. An enantioselective, 31-step synthesis of it was reported in 2012 - an improvement over a previously reported 59-step approach. (Org. Lett. 2012, 14, 4730-4733): WOH Draw the diastereomer that is identical to pladienolide B except for the configuration of each of the chirality centers directly connected to an ester oxygen. X Integrated Problem 07.92d Get help answering Molecular Drawing questions. x Incorrect. Identify the chiral centers adjacent to the ester groups. Pladienolide B is a macrocyclic (large-ring) natural product isolated from an engineered strain of the bacterium Streptomyces platensis. An enantioselective, 31-step synthesis of it was reported in 2012 - an improvement over a previously reported 59-step approach. (Org. Lett. 2012, 14, 4730-4733): WOH Draw the diastereomer that is identical to pladienolide B except for the configuration of each of the chirality centers directly connected to an ester oxygen. X