Item $16$: Question b$.$ Specify substituent positions $($axial or equatorial$)$ in the more stable chair.

c$.$ Estimate the percent of the more stable chair at equlibrium at $25C$

$G=-RTin{K}_{eq},$ where the value for $R$ is $0\mathrm{.}008314k\frac{J}{K^{**}}$mol

Answers:

a$)$ The energy difference is $k\frac{J}{m}ol.$

b$)$ In the more stable chair:

The isopropyl group is in the

position.

The carboxyl group is in the sosition.

c$)$ At $25C$ the equilibrium percent of the more stable chair conformation is approximately