Question: Km and Vmax obtained from the Lineweaver- Burk plot and linear regression analysis for the data in Table 2 are 16.9 mM and 503

Km and Vmax obtained from the Lineweaver- Burk plot and linear regression analysis for the data in Table 2 are 16.9 mM and 503 mM respectively. Compare these values to the values obtained Vmax = 525.3 M/sec Km = 20.70 M . Which method, nonlinear regression or linear regression, is more tolerant to an experimental error? Note that lower substrate concentrations, which often have greater error, have greater effect on the slope of the line in Lineweaver-Burk plot.
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