Question: Learning Activity 1 6 . 3 . You will currently be given actual chemical compounds with their respective pKa values and chemical structures. Determine the

Learning Activity 16.3. You will currently be given actual chemical compounds with their respective pKa values and chemical structures. Determine the buffering range, tell whether the compounds are water-soluble or lipid-soluble, and also tell whether their forms are reabsorbed in the renal tubules or excreted together with the urine based on their structures shown below. Do this in 30 minutes. After the allotted time, class sharing and discussion shall follow.
\table[[Drugs & Description,pKa,Solubility,\table[[Renal Tubular],[Effect]],Buffering Range],[\table[[Ephedrine],[(brain stimulant)]],9.6,,,],[\table[[Ampicillin*],[(antibiotic)]],2.5,,,],[\table[[Allopurinol],[(anti-hyperuricemia)]],9.4,,,],[\table[[Methotrexate*],[(antineoplastic)]],4.8,,,],[\table[[Ibuprofen*],[(anti-inflammatory)]],4.4,,,],[\table[[Ethacrynic acid*],[(diuretic)]],2.5,,,],[\table[[Lidocaine],[(anaesthetic)]],7.9,,,],[\table[[Strychnine],[(pesticide)]],8.0,,,],[\table[[Warfarin*],[(blood thinner)]],5.0,,,],[\table[[Tolazoline],[(vasodilator)]],10.6,,,]]
NOTE: Those with () are weak bases.
 Learning Activity 16.3. You will currently be given actual chemical compounds

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