Nonhydrolyzable GTP Analogs Many enzymes can hydrolyze GTP between the and y phosphates. The GTP analog...
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Nonhydrolyzable GTP Analogs Many enzymes can hydrolyze GTP between the and y phosphates. The GTP analog B,y-imidoguanosine 5'-triphosphate Gpp(NH)p, shown below, cannot be hydrolyzed between the 8 and y phosphates. Predict the effect of microinjection of Gpp (NH)p into a myocyte on the cell's response to -adrenergic stimulation. H 0 I 0-1 -N-P-O-P-0-CH O 0 0 HN HN Gpp(NH)p H H H VH OH OH (8y-imidoguanosine 5'-triphosphate) Nonhydrolyzable GTP Analogs Many enzymes can hydrolyze GTP between the and y phosphates. The GTP analog B,y-imidoguanosine 5'-triphosphate Gpp(NH)p, shown below, cannot be hydrolyzed between the 8 and y phosphates. Predict the effect of microinjection of Gpp (NH)p into a myocyte on the cell's response to -adrenergic stimulation. H 0 I 0-1 -N-P-O-P-0-CH O 0 0 HN HN Gpp(NH)p H H H VH OH OH (8y-imidoguanosine 5'-triphosphate)
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Related Book For
Biochemistry Concepts and Connections
ISBN: 978-0321839923
1st edition
Authors: Dean R. Appling, Spencer J. Anthony Cahill, Christopher K. Mathews
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