Question: Once compounded for I.V. administration in D5W solution at room temperature of 25C, Dilantin (phenytoin sodium) is highly unstable and needs to be administered within

Once compounded for I.V. administration in D5W solution at room temperature of 25C, Dilantin (phenytoin sodium) is highly unstable and needs to be administered within 2 hours. If this I.V. solution, however, is placed in a refrigerator set at 5C, what would you recommend (in hours) as the new shelf-life using the most conservative approach? (Q10 method of shelf-life estimation: t90,t2=t90,t1/Q10(DT/10) ) 0.5 8 12 18

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