Pi symbolizes inorganic phosphate please show and explain the math (6.1) The pKa of the following acid-base
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Pi symbolizes inorganic phosphate
please show and explain the math
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(6.1) The pKa of the following acid-base reactions, HA A- +H*, is approximately 7. H,PO, =HPO?- +H* HADP2 -ADP3 - +H+ HATP3-=ATP- + H* On the assumption that, at pH 7, we may ignore other charged species of these compounds, show that the average charge of P, ADP, and ATP is -1.5, -2.5, and -3.5, respectively, by expressing the probability, TĄ, of the deprotonated state, A-, in terms of pH and pKa, and the average charge in terms of the probabilities of protonated and unprotonated state, TĄ and THA. s TTA (6.1) The pKa of the following acid-base reactions, HA A- +H*, is approximately 7. H,PO, =HPO?- +H* HADP2 -ADP3 - +H+ HATP3-=ATP- + H* On the assumption that, at pH 7, we may ignore other charged species of these compounds, show that the average charge of P, ADP, and ATP is -1.5, -2.5, and -3.5, respectively, by expressing the probability, TĄ, of the deprotonated state, A-, in terms of pH and pKa, and the average charge in terms of the probabilities of protonated and unprotonated state, TĄ and THA. s TTA
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