Question: PLEASE ANSWER ONLY QUESTION G. 1. (50) The pigment-protein complex rhodopsin is found in your retina and is responsible for your sensitive night vision. The

PLEASE ANSWER ONLY QUESTION G. 1. (50) The pigment-protein complex rhodopsin is found in your retina and is responsible for your sensitive night

PLEASE ANSWER ONLY QUESTION G.

1. (50) The pigment-protein complex rhodopsin is found in your retina and is responsible for your sensitive night vision. The active pigment is 11-cis retinal, which undergoes a cis-trans isomerization reaction upon absorption of a photon. cis trants hv All-trans-retinal (attached to opsin, R) 11-cis-retinal (attached to opsin, R) You are measuring this isomerization reaction of the 11-cis retinal in the absence of a photon and obtain the following data shown below. -25 -27 In k1 -Linear (In k1) -29 -31 -33 In k -35 -37 -39 y = -21050x + 30.3 -41 -43 0.0028 0.0029 0.003 0.0031 0.0032 0.0033 0.0034 1/T a. (15) Calculate A, Ea, AH#, AST, AG b. (10) Draw a profile for this reaction. Label all of your axes. Provide a description of the reaction coordinate for this reaction - be explicit. Scanned with CamScanner CS g. (5) You are trying to design an enzyme to catalyze this reaction. Would you design the active site of your enzyme to enhance binding of the substrate or CS the ansition state? Justify your answer in detail. CamScanner

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