PLEASE answer the question$2\mathrm{.}4$ to$2\mathrm{.}9.$Thank you so

much.

$2\mathrm{.}5.$ Draw the curved arrows to complete the reaction mechanism of the following reaction. Start with the itramolecular reaction of chloroethylamine and then react the cyclic product with the primary amine.

$2\mathrm{.}6$ The chloroethylamine has two methylene groups $(C{H}_2{)}_2$ between the nitrogen and the halide group $(C{H}_2{)}_3.$ Explain why.

$2\mathrm{.}7$ Now that you have figured out the reaction mechanism, let's explore the action mechanism of the following drug. Notice that this molecule is composed of two chloroethylarnine groups and therefore can react with two different nucleophiles. Complete the following reaction mechanism.

The above reaction is responsible for the activity of the drug. Because of its ability to react with two nucleophiles, the drug can create a bridge between two biologically active molecules and disrupt their prevent their separation during as 'cross$-$linking'. For example, it can react with two DNA strands and

$2\mathrm{.}9$ The reactivity of nitrogen mustards can be tuned by changing the chemical structure. Compare the reactivity of these two molecules. Which nitrogen is more nucleophilic? Why? Draw a resonance structure to support your