Question: Please answer the question below based on (Vertex Pharmaceuticals: R&D Portfolio Management (A) Case) What approach should be used to make a decision like this?

Please answer the question below based on (Vertex Pharmaceuticals: R&D Portfolio Management (A) Case)

  1. What approach should be used to make a decision like this? How much should Vertex management rely on quantitative methodologies (such as real option valuation) versus more qualitative approaches? How should a company value investment in projects like these, which entail an extremely high degree of uncertainty?

The answer should be comprehensive.

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