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A study was undertaken to determine dose proportionality of an antihistaminic, antiemetic and sedative drug from the tablet dosage form. Following the administration of one tablet containing either 50 or 150 mg of drug, average plasma concentrations were reported from 10 volunteers. Plot the data and, using the plot, determine the following: Time (h) Mean plasma concentration (ng/ml) 50 mg tablet 150 mg tablet 0.25 1.75 5.25 0.5 2.9 8.7 0.75 3.7 11.1 1.0 4.2 12.6 1.5 4.6 13.8 2.0 4.6 13.6 3.0 4.1 12.21 9.85 6.0 2.1 5.11 8.0 1.4 4.15 Calculate the absorption rate constant (Ka) for 150 mg dose (/h) (use the residual method and first 5 points) Question 12 1 pts Calculate the absorption half life, (t1/2)abs, for 50mg dose