Question: Please explain why the answer is B,C and F. Which of the following combination of thermodynamic parameters in an enzyme catalyzed reaction will (1) maximize

Please explain why the answer is B,C and F.
Which of the following combination of thermodynamic parameters in an enzyme catalyzed reaction will (1) maximize Transition State TS binding by the enzyme E AND (2) maximally lower the largest free energy barrier in this enzyme catalyzed reaction pathway. Select all choices that will accomplish the above 2 goals. deltaGb(ETS)=+5kJ/mol deltaGb (ETS)=5kJ/mol deltaGd (ES)=+2kJ/mol deltaGd (ES)=2kJ/mol deltaS (ES)=+0.003kJ/molK deltaS (ES)=0.003kJ/molK
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