Question: PROB 2 6 . 2 2 Living cells homogeneously distributed ( immobilized ) with an agarose gel require glucose to survive. An important aspect of
PROB
Living cells homogeneously distributed immobilized with an agarose gel require glucose to survive. An important aspect of the biochemical system design is the effective diffusion coefficient of glucose species A into the cellimmobilized gel. Consider the experiment shown below where a slab of the cellimmobilized gel of thickness is placed within a
wellmixed aqueous solution of glucose maintained at a concentration of mmo The glucose consumption within the cellimmobilized gel proceeds by a zeroorder process given by
mmomin
The solubilities of the glucose in both water and the gel are the same; that is the concentration of glucose on the water side of the watergel interface is equal to the concentration of glucose on the gel side of the watergel interface. A syringe mounted at the center of the gel carefully excises a tiny sample of the gel for glucose analysis.
Develop a model in final integrated form to predict the concentration profile of glucose within the gel. Be careful with specification of boundary conditions, so that your model is truly predictive and is based only on process input parameters, not measured parameters.
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