Question: PROBLEM STATEMENT The data for the normalized drug concentration change in the toenail ( C A C A , m a x ) on the

PROBLEM STATEMENT The data for the normalized drug concentration change in the toenail (CACA,max) on the y-axis as a function of distance from the nail surface is shown below as a function of time.
a) From this figure, estimate (within an order of magnitude) the diffusion coefficient of the drug within the toenail ). Note: you can make this estimate using any single curve between 2 and 8 hours (though the paper said that the 25hr data set was anomalous).
b) Estimate the time required for the drug to reach the bottom of the toenail if is 1000 microns thick (0.1cm). Does your answer agree with the opening statement that it is hard to get a drug through a toenail by diffusion?
 PROBLEM STATEMENT The data for the normalized drug concentration change in

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