Question: PROBLEM STATEMENT The data for the normalized drug concentration change in the toenail ( C A C A , m a x ) on the
PROBLEM STATEMENT The data for the normalized drug concentration change in the toenail on the axis as a function of distance from the nail surface is shown below as a function of time.
a From this figure, estimate within an order of magnitude the diffusion coefficient of the drug within the toenail Note: you can make this estimate using any single curve between and hours though the paper said that the data set was anomalous
b Estimate the time required for the drug to reach the bottom of the toenail if is microns thick Does your answer agree with the opening statement that it is hard to get a drug through a toenail by diffusion?
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