Propose an efficient synthesis for the following transformation: Solution - Recall from Chapter 11 that there are two questions to ask when approaching a synthesis problem: 1. Is there a change in the carbon skeleton? 2. Is there a change in the position or identity of the functional groups? First consider the carbon skeleton. In this case, there is no change: H H NaCrO7 Now focus on the change in functional groups. In this example, the reactant does not have a functional group at the benzylic position, while the product does. Therefore, we must first introduce functionality at the benzylic position, and there are two ways to do that. OH