QUESTION 1 When calculating sample size requirements to estimate p and we do not know or have an educated guess for p, which of the following is an acceptable value for p: .25 0 .75 .50 1. which one?

QUESTION 2

Of 169 women having breast cancer and a familial risk factor, 27 inherited BRCA1 mutation. Use this information to answer the following:

1) Estimate the prevalence of BRAC1 mutation in women with familial breast cancer.

2) Calculate whether this sample is large enough to use the Normal approximation.

Note: Must show work for full credit. I need enough information that shows you have calculated it.

Don't hand writing