Question 18 What is the difference between a channel protein and a carrier protein? Carrier proteins facilitate movement of substances across a plasma membrane by changing shape to allow solute binding site across the membrane while channel proteins provide a corridor to allow a specific molecule to cross the membrane 1 pts All carrier proteins move molecules (solutes) from low to high concentration while all channel proteins move molecules (solutes) from high to low concentration Channel proteins are peripheral proteins while carrier proteins are integral (transmembrane) proteins Channel proteins can be involved with active transport while carrier proteins cannot